Topics / #science

Science projects on GitHub

Scientific computing languages, tools, and libraries for research and data analysis.

As of , the most-starred Science projects on GitHub are awesome-public-datasets (79.6K stars), julia (49.2K stars) and google-research (38.9K stars). GitHub.Locker tracks 29 Science repositories with 421.3K stars combined. The fastest-growing on October 16 was open-science, with +182 stars in a day.

29Projects
421.3KStars in total
+580Stars in a day
Browse in the catalog →github.com/topics/science ↗

Hot right now

Most stars gained in a day · Oct 16

+182

open-science

aipoch/open-science · ★ 5.1K

AIPOCH Open-Science is an open-source, local-first, model-agnostic AI research workbench that runs scientific AI agents to help with literature review, data analysis, code execution, and producing traceable research reports, tables, and figures.

+148

Deepgraph

billion-token-one-task/Deepgraph · ★ 1K

DeepGraph is the autonomous research agent of JouleBeat, an open-source AI self-improvement (RSI) lab. It reads scientific literature, finds open questions, runs real experiments, and lets the results decide what is true.

+87

math

openai/math · ★ 15K

A public catalogue of 719 mathematical manuscripts grouped into 372 families, written by an internal OpenAI model during evaluations on open research problems. About 42% of top-line results already have Lean formalizations.

+38

learning_research

pengsida/learning_research · ★ 15.2K

A free, open-source guide to doing academic research, written in Chinese by researcher Peng Sida. It distills his research experience in written form so lab newcomers can learn the craft without word-of-mouth training.

The all-time top

29 projects · by stars

  1. #1 · awesomedata/awesome-public-datasets

    awesome-public-datasets

    A huge topic-centric list of high-quality open public datasets, organized by subject area like biology, chemistry, economics, and more.

    79.6K
  2. #2 · JuliaLang/julia

    julia

    Julia is a high-level, high-performance dynamic programming language built for technical and scientific computing, numerical analysis, and machine learning.

    49.2K
  3. #3 · google-research/google-research

    google-research

    A giant monorepo where Google Research dumps the code released alongside its papers and projects - hundreds of independent folders covering different research efforts, not one cohesive product.

    38.9K
  1. 4

    awesome-datascience

    30.2Kacademic/awesome-datascience

    An open-source, community-maintained Data Science repository — essentially a giant curated list of resources (courses, tutorials, algorithms, tools, books, datasets, communities) for learning and applying data science to real-world problems. Around 30k stars, around since 2014.

  2. 5

    COVID-19

    28.9KCSSEGISandData/COVID-19

    The COVID-19 data repository by Johns Hopkins University's Center for Systems Science and Engineering (CSSE) — the case data behind their widely used pandemic Visual Dashboard.

  3. 6

    awesome-python-applications

    18.1Kmahmoud/awesome-python-applications · Jupyter Notebook

    A curated catalog of 426 free, open-source Python applications, arranged by topic with links to each app's repo, homepage, and docs — case studies in successfully shipping Python software.

  4. 7

    mml-book.github.io

    16.1Kmml-book/mml-book.github.io · Jupyter Notebook

    This is the companion website for the book 'Mathematics For Machine Learning', providing exercises and Jupyter notebooks that go along with the book's chapters.

  5. 8

    deepmind-research

    15.2Kgoogle-deepmind/deepmind-research · Jupyter Notebook

    It is Google DeepMind's research repository: implementations and illustrative code that accompany its published papers, released alongside open-source environments and datasets the community can build on.

  6. 9

    learning_research

    15.2Kpengsida/learning_research

    A free, open-source guide to doing academic research, written in Chinese by researcher Peng Sida. It distills his research experience in written form so lab newcomers can learn the craft without word-of-mouth training.

  7. 10

    scipy

    15.1Kscipy/scipy · Python

    SciPy (pronounced 'Sigh Pie') is an open-source Python library for mathematics, science, and engineering.

  8. 11

    math

    15Kopenai/math · Lean

    A public catalogue of 719 mathematical manuscripts grouped into 372 families, written by an internal OpenAI model during evaluations on open research problems. About 42% of top-line results already have Lean formalizations.

  9. 12

    sympy

    15Ksympy/sympy · Python

    SymPy is a computer algebra system (CAS) written entirely in pure Python, used for symbolic mathematics like algebra, calculus, and equation solving.

  10. 13

    Virgilio

    15Kvirgili0/Virgilio · Jupyter Notebook

    A free, open-source initiative that mentors anyone into Data Science: instead of drowning in a chaotic jungle of tutorials, you follow structured learning paths it has put together.

  11. 14

    alphafold

    14.9Kgoogle-deepmind/alphafold · Python

    AlphaFold is Google DeepMind's open source implementation of the AlphaFold v2 inference pipeline, which predicts 3D protein structures from amino acid sequences, plus a work-in-progress AlphaFold-Multimer model for protein complexes.

  12. 15

    seaborn

    14.1Kmwaskom/seaborn · Python

    Seaborn is a Python visualization library based on matplotlib that provides a high-level interface for drawing attractive statistical graphics.

  13. 16

    freemocap

    10.5Kfreemocap/freemocap · TypeScript

    FreeMoCap is a free, open-source motion capture system that uses ordinary cameras (not expensive marker suits) to let researchers, educators, and hobbyists capture human movement in 3D.

  14. 17

    feynman

    10KCompanion-Inc/feynman · TypeScript

    An open source AI research agent: a terminal app that searches papers, runs literature reviews and deep-research workflows, and links every claim back to its sources.

  15. 18

    open-science

    5.1Kaipoch/open-science · TypeScript

    AIPOCH Open-Science is an open-source, local-first, model-agnostic AI research workbench that runs scientific AI agents to help with literature review, data analysis, code execution, and producing traceable research reports, tables, and figures.

  16. 19

    DeepAnalyze

    4.7Kruc-datalab/DeepAnalyze · Python

    DeepAnalyze is an open-source agentic large language model built for fully autonomous data science: it can handle data preparation, analysis, modeling, visualization, and report generation on its own, across structured, semi-structured, and unstructured data sources.

  17. 20

    openscience

    4Ksynthetic-sciences/openscience · TypeScript

    OpenScience is an open-source AI workbench for scientific research: give it a goal and it reads literature, writes and runs code, runs experiments, and writes up what it found.

  18. 21

    NavierStokesAndEuler

    2.1Kopenai/NavierStokesAndEuler · Lean

    This repository contains Lean 4 formalizations (machine-checked formal proofs) of two OpenAI papers: 'Finite time blowup for Navier-Stokes' and 'Finite time blowup for the Euler equation'.

  19. 22

    fermats-last-theorem

    1.3Kanthropics/fermats-last-theorem · Lean

    A complete, machine-checked Lean 4 proof of Fermat's Last Theorem built on Mathlib, following the Frey-Serre-Ribet-Wiles-Taylor-Wiles argument, and cross-checked by two independent kernels.

  20. 23

    desktop-fly

    1.1KDenisSergeevitch/desktop-fly · Swift

    DesktopFly is a 3D fruit fly that lives on your macOS desktop, animated by a live spiking simulation built from the real FlyWire fly-brain connectome (and a motor circuit from the MaleCNS dataset).

  21. 24

    Deepgraph

    1Kbillion-token-one-task/Deepgraph · Python

    DeepGraph is the autonomous research agent of JouleBeat, an open-source AI self-improvement (RSI) lab. It reads scientific literature, finds open questions, runs real experiments, and lets the results decide what is true.

  22. 25

    iudsim

    247THU-iUWLab/iudsim

    IUDSim (Integrated Urban Drainage Simulator) is an urban drainage system simulator built by Tsinghua's iUWLab that tightly couples surface runoff, pipe networks, wastewater treatment, rivers, and human movement into one simulation to model the full event-facility-social-environmental process chain.

  23. 26

    m4-sme-exploration

    245tzakharko/m4-sme-exploration · C

    A research project that microbenchmarks the Scalable Matrix Extension (SME) of Apple's M4 chip, measuring peak compute throughput for common matrix and vector operations and memory transfer rates.

  24. 27

    vistep

    240int64ago/vistep · TypeScript

    vistep.ai is a bilingual collection of short visual stories that explain everyday mechanisms, science and computation, letting you watch a process happen and then experiment with the underlying model.

  25. 28

    OmniScientist

    170Omni-Scientist/OmniScientist · TypeScript

    OmniScientist is an open, omni-modal AI scientist that runs on your own machine. Point it at a folder of data and a research direction, and it forms a hypothesis, writes and runs its own analysis code, reads the resulting figures, and drafts a paper whose every number traces back to a real execution record.

  26. 29

    KISS-Knowledge-Infrastructure-for-Scientific-Simulation

    40lzwei196/KISS-Knowledge-Infrastructure-for-Scientific-Simulation · Python

    KISS is a Knowledge Infrastructure (KI) framework that packages the operational expertise behind running scientific simulation models — how to prepare inputs, judge whether results are physically plausible, and recover from failures — so AI coding agents can run these models reliably, not just know their equations.

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